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Table 4 Final diagnoses of patients referred to the General Medicine Department (n = 408)

From: Investigation of diseases that cause diagnostic difficulty for Japanese general physicians

ICPC-2 Diagnosis Referred by general physicians Referred by other physicians  
n (%) n (%) P value
A. General & Unspecified Unspecified viral infectious disease 9 (5.3) 4 (1.7) 0.047
Conditions within the normal range 8 (4.7) 10 (4.2) 0.811
Adverse reactions to medical products 8 (4.7) 3 (1.3) 0.058
Infectious mononucleosis 3 (1.8) 1 (0.4) 0.070
Other 7 (4.1) 8 (3.3) 0.791
B. Blood, Blood Forming Organs & Immune Mechanism Acute lymphadenitis 4 (2.4) 4 (1.7) 0.498
Adult Still’s disease 0 (0) 3 (1.3) 0.270
Other 7 (4.1) 4 (1.7) 0.213
D. Digestive Reflux esophagitis 3 (1.8) 3 (1.3) 0.695
Acute gastroenteritis 1 (0.6) 3 (1.3) 0.645
Other 16 (9.5) 16 (6.7) 0.351
H. Ear Benign paroxysmal positional vertigo 3 (1.8) 3 (1.3) 0.695
Other 3 (1.8) 3 (1.3) 0.695
K. Cardiovascular Cerebrovascular disease 0 (0) 4 (1.7) 0.145
Other 6 (3.6) 10 (4.2) 0.802
L. Musculoskeletal Cervical spondylosis deformans 3 (1.8) 4 (1.7) 1.000
Rheumatoid arthritis 1 (0.6) 3 (1.3) 0.645
Other 17 (10.1) 22 (9.2) 0.865
N. Neurological Other 10 (5.9) 18 (7.5) 0.558
P. Psychological Anxiety disorder 9 (5.3) 10 (4.2) 0.638
Mood disorder 6 (3.6) 14 (5.9) 0.356
Adjustment disorder 5 (3.0) 6 (2.5) 0.767
Somatoform disorder 4 (2.4) 19 (7.9) 0.016
Delusional disorder 1 (0.6) 4 (1.7) 0.409
Hypochondria 0 (0 ) 6 (2.5) 0.044
Other 6 (3.6) 10 (4.2) 0.802
R. Respiratory Cough variant asthma 0 (0) 3 (1.3) 0.270
Other 11 (6.5) 7 (2.9) 0.092
S. Skin Cellulitis 1 (0.6) 5 (2.1) 0.408
Stasis dermatitis 0 (0) 3 (1.3) 0.270
Other 2 (1.2) 2 (0.8) 1.000
T. Endocrine/Metabolic & Nutritional Graves’ disease 3 (1.8) 2 (0.8) 0.653
Other 5 (3.0) 6 (2.5) 0.767
U. Urological Pyelonephritis 0 (0) 4 (1.7) 0.145
Other 2 (1.2) 2 (0.8) 1.000
X. Female Genital (including breasts) Other 3 (1.8) 4 (1.7) 1.000
Z. Social Problems Other 0 (1.4) 3 (1.3) 0.270
Other Uncertain diagnosis 2 (1.2) 3 (1.3) 1.000
  1. (Diagnosis with more than three patients in any group are shown, and diagnosis with less than two are included as other in its category).
  2. Date was analysed by the Fisher’s exact test and post hoc Bonferroni test, and the significant level was set at P < 0.0013.
  3. General physicians: physicians working at general internal medicine clinics.
  4. Other physicians: physicians working at specialist clinics or hospital physicians.
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